How to open a med spa: what the rules actually require
Opening a med spa is governed less by business licensing than by medical law. In most states, injecting a neuromodulator or filler is the practice of medicine, which means four things decide whether — and how — you can open: who may own the business, which physician must supervise it, what exam must happen before a patient is treated, and who is allowed to hold the syringe. Each is set by state law and each changes through legislation and licensing-board action.
Below is what each of those four requires, in the states where we have verified the rules against the primary source. Every statement is linked to the statute, rule, or board document it came from, and dated. This is regulatory monitoring and reference — not legal advice.
What this page covers. 77 rules, each cited to a primary source, across 5 states: Arizona, California, Florida, Indiana, Texas. We monitor all 50 state legislatures daily, but we only publish a rule here once we have verified it against the source document — so this list grows as states are verified, and it never claims a state we have not read. Most recent verification: Jul 26, 2026.
1. Can you own a med spa?
Who is allowed to own the business, and in what corporate form?
Arizona
Ownership & corporate practice of medicineUnlike strict-CPOM states, Arizona’s Medical Practice Act regulates individual licensees rather than business ownership.
Arizona has no statute prohibiting non-physician ownership of a medical practice; the Medical Practice Act regulates individual licensees, and clinical decision-making must stay with licensees under the standard-of-care rules.
A.R.S. §32-1401 · verified Jul 26, 2026
If a practice organizes as a professional corporation, non-licensed persons may hold up to 49% of the voting shares (unless the licensing authority prescribes a different percentage).
A.R.S. §10-2220(A)(4) · verified Jul 26, 2026
California
Ownership & corporate practice of medicineCalifornia strongly bars the corporate practice of medicine. This is the opposite of a permissive-ownership state.
Corporations and other artificial legal entities have no professional rights, privileges, or powers — laypersons and lay entities may not own any part of a medical practice or control clinical decisions.
Cal. Bus. & Prof. Code §2400 · verified Jul 26, 2026
The compliant structure is a professional medical corporation under the Moscone-Knox Act: a majority of shares must be held by California-licensed physicians, only enumerated licensed health professionals may hold shares (up to 49% in aggregate), and no lay person may hold any stock.
Cal. Corp. Code §13401.5(a) · verified Jul 26, 2026
Florida
Ownership & corporate practice of medicineFlorida has no strict corporate-practice-of-medicine ban. Non-physician ownership is instead gated by the Health Care Clinic Act.
Unlike some states, Florida does not broadly prohibit non-physician ownership of a medical practice or med spa; ownership is governed by the Health Care Clinic Act rather than a corporate-practice-of-medicine prohibition.
Fla. Stat. §400.990 · verified Jul 26, 2026
An entity that provides health-care services and bills for reimbursement is a “clinic” that must be licensed by AHCA to operate — each location licensed separately — unless it qualifies for an exemption.
Fla. Stat. §400.991(1)(a) · verified Jul 26, 2026
Indiana
Ownership & corporate practice of medicineIndiana is comparatively permissive and does not impose a strict corporate-practice-of-medicine ban.
An employment or other contractual relationship between an entity and a licensed physician is not the unlawful practice of medicine, as long as the entity does not direct or control the physician’s independent medical acts, decisions, or judgment. So a non-physician-owned entity may employ physicians without controlling their clinical judgment.
Ind. Code §25-22.5-1-2(c) · verified Jul 26, 2026
Texas
Ownership & corporate practice of medicineTexas follows the corporate-practice-of-medicine doctrine, derived from the Medical Practice Act’s licensure requirement rather than a single titled statute.
A person may not practice medicine in Texas unless licensed by the Board. As a result, a general business corporation or an unlicensed individual cannot practice medicine or employ physicians in a way that controls their medical judgment.
Tex. Occ. Code §155.001 · verified Jul 26, 2026
One recognized structure is a Board-certified nonprofit health organization (a “5.01(a)” corporation) that is organized solely by Board-licensed physicians.
Tex. Occ. Code §162.001 · verified Jul 26, 2026
2. The medical oversight you will need
Which physician relationship the state requires, and what they must do.
Arizona
Physician supervision & delegationArizona regulates individual licensees, not procedures by name; delegation flows through the Medical Practice Act.
A medical assistant is an unlicensed person who may perform delegated tasks commensurate with their training but may not diagnose or design/modify a treatment program. Failing to adequately supervise medical assistants or other personnel is itself unprofessional conduct.
A.R.S. §32-1401 · verified Jul 26, 2026
A medical assistant may administer injections and draw specimens only under the “direct supervision” of a physician, PA, or NP — the supervisor present in the same room or office suite.
A.R.S. §32-1456 · verified Jul 26, 2026
California
Physician supervision & delegationIn California, using prescriptive drugs (Botox, fillers) and prescriptive/energy devices (lasers, IPL) for cosmetic reasons IS the practice of medicine.
A physician may delegate injectable and laser procedures only to appropriately licensed personnel — registered nurses, nurse practitioners, or physician assistants — under genuine supervision. Unlicensed staff (including medical assistants) and improperly licensed staff (estheticians, cosmetologists, LVNs) may not perform them, regardless of training. A “paper” medical-director arrangement is aiding and abetting the unlicensed practice of medicine.
Cal. Bus. & Prof. Code §2052; Medical Board of California — Medical Spas guidance · verified Jul 26, 2026
For an elective cosmetic laser or IPL procedure performed by a licensed provider, a trained physician must be “immediately available” — reachable without delay and able to direct throughout the procedure.
Cal. Code Regs. tit. 16, §1364.50 · verified Jul 26, 2026
Florida
Physician supervision & delegationFlorida regulates cosmetic procedures through the physician’s duty to supervise and to delegate only to qualified people — not a single “cosmetic procedures” statute.
Delegating professional responsibilities to a person the physician knows (or should know) is not qualified by training, experience, or licensure is a disciplinable offense.
Fla. Stat. §458.331(1)(w) · verified Jul 26, 2026
Aiding, assisting, procuring, or advising an unlicensed person to practice medicine is a ground for discipline against the physician.
Fla. Stat. §458.331(1)(f) · verified Jul 26, 2026
Indiana
Physician supervision & delegationIndiana defines the practice of medicine broadly; injectables and energy procedures are the practice of medicine unless performed by a licensed professional within scope or under proper delegation.
The “practice of medicine” includes prescribing or administering any form of treatment and procedures that cut, burn, or vaporize tissue by mechanical means, laser, or penetration of the skin — the statutory basis for treating cosmetic injectables and energy-device procedures as medicine.
Ind. Code §25-22.5-1-1.1 · verified Jul 26, 2026
Texas
Physician supervision & delegationCosmetic injections, fillers, and cosmetic laser use are medical acts a physician may delegate under supervision. As of Jan 9, 2025 the governing Board rules are in 22 TAC Chapter 169.
A Texas physician may delegate a medical act — including cosmetic injections, dermal fillers, and cosmetic laser use — to a qualified, properly trained person acting under the physician’s supervision, where a reasonable and prudent physician would find it consistent with sound medical judgment. The delegating physician remains responsible for the delegated act.
Tex. Occ. Code §157.001 · verified Jul 26, 2026
The Texas Medical Board classifies nonsurgical medical cosmetic procedures — including the injection of medications or substances for cosmetic purposes and the use of a prescription medical device for cosmetic purposes — as the practice of medicine that may be properly delegated and supervised.
22 TAC §169.25 · verified Jul 26, 2026
3. What has to happen before a patient is treated
The exam or provider-patient relationship required before the first injection.
Arizona
Good-faith examinationArizona has no statute that names a “good-faith exam”; the requirement derives from the standard of care and prescribing law.
Because Botox and fillers are prescription drugs/devices, they require a valid order from an authorized prescriber acting within the standard of care; failing to meet the standard of care is unprofessional conduct.
A.R.S. §32-1401(27) · verified Jul 26, 2026
Arizona’s telehealth statute allows the provider-patient relationship to be established and prescribing to occur via telehealth with documented informed consent; a board may not require a prior in-person exam except for Schedule II drugs (which Botox and fillers are not).
A.R.S. §36-3602 · verified Jul 26, 2026
California
Good-faith examinationCalifornia requires an appropriate good-faith exam before prescriptive drugs or devices are used — and it may not be delegated to an RN.
Prescribing, dispensing, or furnishing a dangerous drug (such as Botox or fillers) without an appropriate prior examination and a medical indication is unprofessional conduct.
Cal. Bus. & Prof. Code §2242(a) · verified Jul 26, 2026
Per the Medical Board, the required prior examination may NOT be delegated to a registered nurse — a physician (or an NP or PA under standardized procedures) must perform the good-faith exam and issue a patient-specific order before an RN performs the injection or laser treatment.
Medical Board of California — Medical Spas guidance · verified Jul 26, 2026
Florida
Good-faith examinationFlorida has no statute literally titled “good-faith exam.” The requirement is built from prescribing-practice and standard-of-care law.
Because Botox and dermal fillers are prescription (legend) drugs, a valid physician evaluation supporting the treatment is required; prescribing or administering a legend drug other than in the course of the physician’s professional practice is a disciplinable offense.
Fla. Stat. §458.331(1)(q) · verified Jul 26, 2026
A remote (telehealth) evaluation must meet the same standard of care as an in-person visit; a telehealth provider who conducts a patient evaluation sufficient to diagnose and treat is not separately required to perform a prior in-person exam.
Fla. Stat. §456.47(2) · verified Jul 26, 2026
Indiana
Good-faith examinationBotox and fillers are legend (prescription) drugs, so a valid prescriber and a lawful prescribing relationship are required.
A prescriber may issue a prescription without a prior in-person exam only if the applicable standard of care is satisfied, the prescription is within the prescriber’s scope, and a valid provider-patient relationship has been established — including identity/location verification, informed consent, a medical history sufficient to establish a diagnosis, and discussion of the diagnosis and risks/benefits.
Ind. Code §25-1-9.5-7, §25-1-9.5-8 · verified Jul 26, 2026
Texas
Good-faith examinationTexas does not use the phrase “good-faith exam.” The operative requirement is establishing a practitioner-patient relationship before the delegated act.
Before a delegated cosmetic act, a practitioner-patient relationship must be established by a physician, or by a PA or APRN acting under the physician’s delegation, and an adequate medical record must be maintained. The identity and title of the person who will perform the act must be disclosed to the patient.
22 TAC §169.26 · verified Jul 26, 2026
A physician, PA, or APRN must be onsite during the procedure or immediately available for emergency consultation, and at least one person trained in basic life support must be present while the patient is onsite.
22 TAC §169.26 · verified Jul 26, 2026
4. Who may actually inject
Whether an RN, NP, or PA may treat, and under whose supervision.
Arizona
RN / NP scope for injectablesThe Arizona rules on this, verbatim from the source:
A registered nurse may administer injectables pursuant to a valid order or delegation from an authorized prescriber, but is not an independent prescriber.
A.R.S. §32-1601(24) · verified Jul 26, 2026
A registered nurse practitioner may diagnose and may prescribe, administer, and dispense legend drugs and devices within the NP scope — so an NP may both order and administer cosmetic injectables.
A.R.S. §32-1601(23) · verified Jul 26, 2026
California
RN / NP scope for injectablesThe California rules on this, verbatim from the source:
A registered nurse may inject Botox/fillers or operate a laser only after a physician, NP, or PA has performed the good-faith exam and issued a patient-specific order, and only within standardized procedures in an organized health care system — not as an independent salon practice.
Cal. Bus. & Prof. Code §2725 · verified Jul 26, 2026
Under standardized procedures, an NP (unlike an RN) may be delegated the prior good-faith exam and the ordering of the drug or device. AB 890’s autonomous-NP categories do not carve out or specially authorize aesthetic practice, and an autonomous NP remains bound by the good-faith-exam and CPOM rules.
Cal. Bus. & Prof. Code §2837.103 · verified Jul 26, 2026
Florida
RN / NP scope for injectablesThe Florida rules on this, verbatim from the source:
A registered nurse may administer medications and treatments — including injectables — as prescribed or authorized by a duly licensed practitioner. RNs are not independent prescribers.
Fla. Stat. §464.003 · verified Jul 26, 2026
An APRN performs authorized functions within the framework of an established protocol maintained on-site, unless the APRN is registered for autonomous practice.
Fla. Stat. §464.012(3) · verified Jul 26, 2026
APRN autonomous practice (without a supervising physician) is available only in primary care — family medicine, general pediatrics, and general internal medicine — which does not encompass cosmetic/aesthetic injectable practice.
Fla. Stat. §464.0123 · verified Jul 26, 2026
Indiana
RN / NP scope for injectablesThe Indiana rules on this, verbatim from the source:
Registered nursing includes executing regimens delegated by a physician or other authorized prescriber. An RN does not independently prescribe; an RN administers injectables pursuant to a valid order within the delegated regimen.
Ind. Code §25-23-1-1.1 · verified Jul 26, 2026
An advanced practice registered nurse may obtain independent prescriptive authority only through the Board of Nursing’s program, renewed on two-year cycles.
Ind. Code §25-23-1-19.5 · verified Jul 26, 2026
A collaborating physician may delegate authority to a physician assistant to prescribe legend drugs and medical devices.
Ind. Code §25-27.5-5-6 · verified Jul 26, 2026
Texas
RN / NP scope for injectablesThe Texas rules on this, verbatim from the source:
A registered nurse who is not an APRN (and an LVN) may not perform medical diagnosis or prescribe, but may carry out a delegated medical act — such as administering a cosmetic injection ordered by an appropriately licensed practitioner — when the Board of Nursing’s criteria are met: documented competency/education, written policies and guidelines, an order from an appropriate licensed practitioner, and available medical and nursing support.
Tex. BON Position Statement 15.11 · verified Jul 26, 2026
For laser therapy performed by RNs or LVNs, the Board of Nursing directs nurses to the Texas Medical Board’s delegation rule for nonsurgical cosmetic procedures and to the Health & Safety Code’s laser provisions.
Tex. BON Position Statement 15.9 · verified Jul 26, 2026
5. What you can actually put in the syringe
The other half of opening a med spa is what you may legally stock. GLP-1s and peptides are the two areas that move fastest: whether a compounded version is permitted turns on FDA shortage status and the 503A Bulks List, both of which change on federal timelines with no notice to practices. A business plan built on a compounded product that loses its basis is the most common way a new med spa is caught out.
The substance tracker lists every GLP-1 and peptide we monitor with its current federal standing, each linked to the government document it came from and dated.
Check current substance status →6. What changed recently
Federal actions apply in every state, including yours before you have opened.
- Federal RegisterJul 30, 2026
FDA / Federal Register Notice: Outsourcing Facility Fee Rates for Fiscal Year 2027
- FDA Warning LetterJul 8, 2026
- Federal RegisterJun 26, 2026
- FDA Warning LetterJun 23, 2026
- FTC EnforcementJun 12, 2026
Opening a med spa — FAQ
- Do I need a medical director or supervising physician to run a med spa?
- In most states, yes. Aesthetic procedures like injectables and lasers are considered the practice of medicine, which typically requires a physician owner, a medical director, or a supervising/delegating physician relationship. The specifics — ownership rules, delegation, chart review, and how often the physician must be involved — vary by state and change through legislation, which is exactly what Med Spa Radar tracks.
- What is a good-faith exam requirement for med spas?
- A good-faith exam (GFE) is a clinical evaluation required before a patient is treated — for example before Botox or filler — to establish a valid provider-patient relationship and a treatment order. States increasingly regulate who may perform the GFE and whether it can be done over telehealth. New GFE rules are one of the most common scope-of-practice changes we surface.
- Can a nurse, NP, or PA inject Botox or filler without a doctor present?
- It varies widely by state. Some states grant nurse practitioners broad independent authority; others require a delegating or supervising physician, an established good-faith exam, or physician availability. Because these scope-of-practice rules change through state legislation and licensing-board action, the safe answer is state-specific — and it moves. Med Spa Radar monitors all 50 states and DC for exactly these changes.
- Can med spas legally compound or sell semaglutide and tirzepatide?
- It depends on two things that change frequently: whether the drug is on the FDA shortage list, and your state’s rules. Under federal law (sections 503A and 503B), a compounder generally may not make a copy of a commercially available drug — being on the FDA shortage list has been the main exception that allowed compounded semaglutide and tirzepatide. When the FDA declared those shortages resolved, the basis for compounded versions narrowed sharply. Med Spa Radar tracks FDA shortage status and state action daily so you know when it changes. This is regulatory monitoring, not legal advice.
- Can med spas compound peptides like BPC-157, KPV, or TB-500?
- It depends on whether the peptide is on the FDA’s 503A Bulks List — and as of the July 2026 Pharmacy Compounding Advisory Committee (PCAC) meetings, none of the headline peptides are. PCAC recommended further review of BPC-157, KPV, TB-500, and MOTS-c, but a recommendation is not a legal status change: FDA is not bound by it, and actually permitting 503A compounding requires notice-and-comment rulemaking, commonly 8–12 months. So these remain not compoundable under 503A today. FDA has separately scheduled a further PCAC meeting by the end of February 2027 for five more peptides (GHK-Cu, Melanotan II, LL-37, Dihexa, PEG-MGF). We track each substance’s current standing, with its government source and date, on the Med Spa Radar substance tracker. This is regulatory monitoring, not legal advice.
- How does a med spa stay compliant with constantly changing regulations?
- The practical challenge is awareness: rules change through hundreds of state bills plus FDA and Federal Register activity every session, and a single missed change can put a license or the business at risk. Med Spa Radar monitors all of those sources daily, scores each change for impact, and tells you in plain language what changed and what to do — so compliance starts with knowing first.
- Is Med Spa Radar legal or compliance advice?
- No. Med Spa Radar is regulatory monitoring, not legal, medical, or compliance advice. We surface relevant changes early and link you to the primary source so you and your counsel can act on them. Always verify against the primary source and consult qualified counsel before making compliance decisions.
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Med Spa Radar is regulatory monitoring and reference, not legal, medical, or compliance advice. Verify against the primary source and consult qualified counsel before making compliance decisions. · All states →