Missouri scope of practice for med spas
Who may perform which procedures, and under what supervision, by state. Below are the Missouri rules that govern it, each linked to its primary source.
RN / NP scope for injectables in Missouri
An advanced practice registered nurse in Missouri is a person licensed under the nursing chapter to practice advanced practice nursing as a certified clinical nurse specialist, certified nurse midwife, certified nurse practitioner or certified registered nurse anesthetist. Prescribing runs through the written arrangement on the face of these claims: a collaborative practice arrangement MAY delegate to an APRN the authority to administer, dispense or prescribe drugs and provide treatment, and may delegate authority over controlled substances in Schedules III, IV and V and Schedule II hydrocodone. The delegation runs through the written arrangement described in the supervision section of this reference; whether any independent route exists elsewhere in the nursing chapter is not surveyed by these claims. Physician assistants are bounded differently again: the statute enumerates their scope of practice as consisting ONLY of nine listed services and procedures, and says a physician assistant may not prescribe any drug, medicine, device or therapy except pursuant to a collaborative practice arrangement.
"Advanced practice registered nurse" or "APRN", a person who is licensed under the provisions of this chapter to engage in the practice of advanced practice nursing as a certified clinical nurse specialist, certified nurse midwife, certified nurse practitioner, or certified registered nurse anesthetist.
Mo. Rev. Stat. §335.016(2) · verified Sep 3, 2026
Collaborative practice arrangements, which shall be in writing, may delegate to a registered professional nurse the authority to administer, dispense or prescribe drugs and provide treatment if the registered professional nurse is an advanced practice registered nurse as defined in subdivision (2) of section 335.016.
Mo. Rev. Stat. §334.104.2(1) · verified Sep 3, 2026
Collaborative practice arrangements may delegate to an advanced practice registered nurse, as defined in section 335.016, the authority to administer, dispense, or prescribe controlled substances listed in Schedules III, IV, and V of section 195.017, and Schedule II - hydrocodone.
Mo. Rev. Stat. §334.104.2(1) · verified Sep 3, 2026
"Certified clinical nurse specialist", a registered nurse who is currently certified as a clinical nurse specialist by a nationally recognized certifying board approved by the board of nursing.
Mo. Rev. Stat. §335.016(5) · verified Sep 3, 2026
The scope of practice of a physician assistant shall consist only of the following services and procedures: taking patient histories; performing physical examinations of a patient; performing or assisting in the performance of routine office laboratory and patient screening procedures; performing routine therapeutic procedures; recording diagnostic impressions and evaluating situations calling for attention of a physician to institute treatment procedures; instructing and counseling patients regarding mental and physical health using procedures reviewed and approved by a collaborating physician; assisting the supervising physician in institutional settings; assisting in surgery; and performing such other tasks not prohibited by law under the collaborative practice arrangement with a licensed physician as the physician assistant has been trained and is proficient to perform.
Mo. Rev. Stat. §334.735.2 · verified Sep 3, 2026
Physician assistants shall not prescribe any drug, medicine, device or therapy unless pursuant to a collaborative practice arrangement in accordance with the law.
Mo. Rev. Stat. §334.735.4 · verified Sep 3, 2026
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MedSpaRadar is regulatory monitoring and reference: it summarizes public laws, regulations and agency actions and links each to its source. It is not legal, medical, or compliance advice, and using it creates no attorney-client relationship. A summary can lag its source or leave out detail, and monitoring itself can be interrupted — so an absence of alerts means nothing reached you, not that nothing happened. Read the cited source, check its effective date, and confirm any change to your operations or clinical practice with qualified health-law counsel and your medical director.