Can a nurse practitioner treat without a supervising physician in Missouri?

Who treats · part of The Practice Perimeter

"Advanced practice registered nurse" or "APRN", a person who is licensed under the provisions of this chapter to engage in the practice of advanced practice nursing as a certified clinical nurse specialist, certified nurse midwife, certified nurse practitioner, or certified registered nurse anesthetist.

Mo. Rev. Stat. §335.016(2) · verified Sep 3, 2026 · regulatory monitoring, not legal advice

The rest of what Missouri says on this

Every other rule we have verified under rn / np scope for injectables, each linked to its primary source.

  • Collaborative practice arrangements, which shall be in writing, may delegate to a registered professional nurse the authority to administer, dispense or prescribe drugs and provide treatment if the registered professional nurse is an advanced practice registered nurse as defined in subdivision (2) of section 335.016.

    Mo. Rev. Stat. §334.104.2(1) · verified Sep 3, 2026

  • Collaborative practice arrangements may delegate to an advanced practice registered nurse, as defined in section 335.016, the authority to administer, dispense, or prescribe controlled substances listed in Schedules III, IV, and V of section 195.017, and Schedule II - hydrocodone.

    Mo. Rev. Stat. §334.104.2(1) · verified Sep 3, 2026

  • "Certified clinical nurse specialist", a registered nurse who is currently certified as a clinical nurse specialist by a nationally recognized certifying board approved by the board of nursing.

    Mo. Rev. Stat. §335.016(5) · verified Sep 3, 2026

  • The scope of practice of a physician assistant shall consist only of the following services and procedures: taking patient histories; performing physical examinations of a patient; performing or assisting in the performance of routine office laboratory and patient screening procedures; performing routine therapeutic procedures; recording diagnostic impressions and evaluating situations calling for attention of a physician to institute treatment procedures; instructing and counseling patients regarding mental and physical health using procedures reviewed and approved by a collaborating physician; assisting the supervising physician in institutional settings; assisting in surgery; and performing such other tasks not prohibited by law under the collaborative practice arrangement with a licensed physician as the physician assistant has been trained and is proficient to perform.

    Mo. Rev. Stat. §334.735.2 · verified Sep 3, 2026

  • Physician assistants shall not prescribe any drug, medicine, device or therapy unless pursuant to a collaborative practice arrangement in accordance with the law.

    Mo. Rev. Stat. §334.735.4 · verified Sep 3, 2026

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← All Missouri rules and changes · MedSpaRadar is regulatory monitoring and reference, not legal, medical, or compliance advice. Verify against the linked primary source and consult qualified counsel before acting — rules change and turn on your specific facts. Legislative data via LegiScan (CC BY 4.0).