Can a registered nurse inject Botox or filler in Colorado?
Who treats · part of The Practice Perimeter
Short answer
The cited rules do not settle this — executing delegated medical functions is lawful nursing for an RN, but no cited rule names injectables. They do settle that an RN cannot prescribe the product: that authority is granted only to APRNs on the registry.
Colorado APRNs prescribe only with separate, earned authority: THREE YEARS of clinical experience, then 750 HOURS of documented prescribing mentorship. Two details matter to a med spa — remote mentoring must be SYNCHRONOUS (e-mail does not count), and a mentor may not require payment or employment as the price of the relationship.
Drawn from 7 verified rules in this section · regulatory monitoring, not legal advice
- Colo. Rev. Stat. § 12-255-112(1)(a), (3)(a) · Sep 2, 2026
- Colo. Rev. Stat. § 12-255-112(4)(a) · Sep 2, 2026
- Colo. Rev. Stat. § 12-255-112(4)(b)(I)(A) · Sep 2, 2026
- Colo. Rev. Stat. § 12-255-112(4)(b)(I)(B) · Sep 2, 2026
- Colo. Rev. Stat. § 12-255-112(4)(b)(I)(C) · Sep 2, 2026
- Colo. Rev. Stat. § 12-240-121(1)(bb) · Sep 2, 2026
- Colo. Rev. Stat. § 12-240-114.5(2)(a) · Sep 8, 2026
Related Colorado rules
Prescriptive authority is not part of APRN registration; the board grants it separately to an APRN on the advanced practice registry whose license is in good standing without disciplinary sanctions and who has met the requirements of § 12-255-112. Authority extends to prescribing “to provide treatment to clients within the role and population focus of the advanced practice registered nurse” — so a pediatric focus is not a warrant to prescribe cosmetically to adults.
Colo. Rev. Stat. § 12-255-112(1)(a), (3)(a) · verified Sep 2, 2026
An APRN applying for prescriptive authority must provide the board with an appropriate graduate degree, education in controlled substances and prescription drugs, national certification, professional liability insurance, inclusion on the advanced practice registry, and “a signed attestation stating that the advanced practice registered nurse has completed at least three years of combined clinical work experience as a professional nurse or as an advanced practice registered nurse.”
Colo. Rev. Stat. § 12-255-112(4)(a) · verified Sep 2, 2026
How other states answer this
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Related Colorado questions
- Can a nurse practitioner treat without a supervising physician in Colorado?
- Can a physician assistant inject or prescribe in Colorado?
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← All Colorado rules and changes · MedSpaRadar is regulatory monitoring and reference: it summarizes public laws, regulations and agency actions and links each to its source. It is not legal, medical, or compliance advice, and using it creates no attorney-client relationship. A summary can lag its source or leave out detail, and monitoring itself can be interrupted — so an absence of alerts means nothing reached you, not that nothing happened. Read the cited source, check its effective date, and confirm any change to your operations or clinical practice with qualified health-law counsel and your medical director. Legislative data via LegiScan (CC BY 4.0).