Does a med spa have to register or hold a license in Wyoming?

Short answer
Not directly — the cited rules create no med spa license; a Board salon license is required for any place where cosmetology is practiced, and medical services in a salon must sit in a separate room and be performed only by licensed medical staff.

Wyoming licenses the PREMISES through the cosmetology board, and the board’s own rules put a PRICE on it. A “salon” means any place Licensed Under The Act in which cosmetology is practiced, and no person, association, partnership or corporation may operate a salon without first securing a license from the Board — the application goes in at least fifteen days before opening, with the fees, a completed inspection sheet and a detailed floor plan. The statute delegates the amounts to the board, and the board’s fee chapter names them: a salon application fee of $225.00, a salon license of $75.00 per year, a personal license (cosmetologist, nail technician, esthetician, hairstylist or instructor) of $48.00 per year and an independent contractor license of $75.00 per year, all non-refundable. The salon rules also draw the med spa line inside the premises: medical services are listed among the services allowed in a salon that the board does not regulate, but all medical services and treatments must be offered in a separate room from cosmetology services and only licensed medical staff may perform them. On the drug-supply side the Board of Pharmacy’s general practice rules answer the compounded-GLP-1 question directly: a prescription may not be dispensed to a practitioner on an order that is not issued for one specific patient, and an order for “office use” is not a valid order; “compounding” excludes work done in an FDA-registered outsourcing facility and includes anticipatory preparation based on routine, regularly observed prescribing patterns. The Act’s exemption for licensed physicians and other named professionals is set out in the supervision section of this reference; these claims do not themselves carry it.