Does a med spa have to register or hold a license in Oregon?

Short answer
The cited rules do not settle this — they define a "facility" as an establishment providing services in a field of practice and set facility license fees ($140 application, $155 per year), but none of them imposes the duty to hold one or any med spa license.

Oregon prices the premises in the Health Licensing Office’s fee rule rather than in the cosmetology chapter, which defines the “facility” — an establishment operated on a regular or irregular basis for the purpose of providing services in one or more fields of practice — and stops there. The fees, established by the Office in consultation with the Board, are: a facility license application of $140 and original issuance of $155 for one year, renewed at $155 for one year; a practitioner certificate application of $30 per field of practice, original issuance of $35 for two years and renewal of $65 for two years. These claims describe cosmetology facility licensure and its cost; they do not address med-spa or medical facility registration, and the chapter’s definition of esthetics, which draws the line at medical diagnosis or treatment, is set out in the supervision section of this reference. On compounded drugs the Pharmacy Act’s only provision on record here is definitional: “manufacture” does not include the preparation or compounding of a drug by a practitioner as an incident to administering or dispensing it in the course of professional practice. That is what the statute says; these claims do not survey the Board of Pharmacy’s compounding rules, and whether a particular compounded semaglutide or tirzepatide product may be supplied to or administered in a med spa is not answered by them.