Mississippi med spa & injectable regulations
What’s changing for med spas and injectors in Mississippi — GLP-1 compounding, scope-of-practice, and enforcement — plus the federal FDA and Federal Register actions that apply in Mississippi. MedSpaRadar monitors it all and tells you, in plain language, what changed and what to do.
Opening a med spa in Mississippi? Start with who may own one, the medical director rules, and who may inject in Mississippi →
Latest Mississippi changes
No new Mississippi changes in the last 19 months. We scan the Mississippi legislature daily and nothing med-spa-relevant has moved since Feb 13, 2025. The Mississippi legislature is in session (2026 1st Special Session). Bills can move at any time. A quiet state is good news — the record below still applies, and the federal changes further down apply to every Mississippi practice today.
Did not become law (1)
These were introduced and failed. They are kept here because knowing a bill died is worth as much as knowing one passed — and because the same subject often returns in the next session.
- CAUTIONDeadLegiScanFeb 13, 2025
MS HB1430: Prescription drugs; prohibit licensing boards from prohibiting practitioners from prescribing for off-label use.
Mississippi off-label prescribing bill; died on the calendar.
Every Mississippi bill we hold died without becoming law. That is a real finding, not an empty page — nothing changed for Mississippi practices.
Federal changes that apply in Mississippi
FDA and Federal Register actions are nationwide — they govern Mississippi practices too.
- MONITORFEDERALPrimary Source MonitoringSep 21, 2026
Primary Source Monitoring: Former Connecticut Resident Guilty of Operating Websites to Illegally Sell Misbranded and Unapproved Drugs
Caution urged due to recent conviction for selling misbranded drugs.
- MONITORFEDERALPrimary Source MonitoringSep 17, 2026
Primary Source Monitoring: Korea Filler Experts - 718706 - 11/03/2025
FDA warns koreafillerexperts.com over unapproved, misbranded injectable botulinum toxin.
- CRITICALFEDERALFDA Device RecallSep 16, 2026
FDA device recall (Class II): Product Name: DermaV Laser System Model/Catalog Number: DermaV Medical laser device that delivers pulsed laser energy a…
FDA recalls DermaV Laser System; check for safety compliance.
- MONITORFEDERALPrimary Source MonitoringSep 16, 2026
Primary Source Monitoring: FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize
FDA updates compounding guidelines as GLP-1 supplies stabilize.
- MONITORFEDERALPrimary Source MonitoringSep 15, 2026
Primary Source Monitoring: Hefner v. Rock Valley Compounding Pharmacy, LLC (3:26-cv-01298) — District Court, S.D. Illinois
Legal case filed affecting compounding pharmacy standards.
- MONITORFEDERALPrimary Source MonitoringSep 9, 2026
Primary Source Monitoring: Human Drug Compounding Policies and Rules
FDA's compounding policy index adds a September 2026 neonatal nutrition guidance.
What we monitor in Mississippi
- Mississippi legislature — bills on injectables, GLP-1s & scope of practice
- U.S. FDA — enforcement, warning letters, recalls, shortages
- Federal Register — new rules on compounding & aesthetics
Mississippi med spa questions, answered from statute
The same verified record, asked the way operators actually ask it — who may own one, who may inject, what the supervising physician has to do. 21 questions have a cited Mississippi answer today.
Browse the 21 Mississippi questions →Mississippi med-spa compliance rules
70 rules across 7 topics — physician delegation, the good-faith exam, ownership & corporate practice of medicine, RN/NP scope, med-spa registration, advertising, and enforcement — each linked to its primary source. Reference and monitoring, not legal advice.
Physician supervision & delegation13 cited rules
The statute defines the practice of medicine as suggesting, recommending, prescribing, or directing any drug, medicine, appliance, or other agency for the cure, relief, or palliation of any ailment for compensation, and requires a license from the State Board of Medical Licensure before practicing.
- All 13 cited rules: Mississippi medical director requirements →
- Does a med spa in Mississippi need a medical director? →
- What must the supervising physician actually do in Mississippi? →
- Who may operate a cosmetic laser in Mississippi? →
- Can a medical assistant give injections in Mississippi? →
- May an esthetician or laser technician perform microneedling in Mississippi? →
Good-faith examination7 cited rules
A valid physician-patient relationship for telemedicine requires verifying the patient’s identity, an appropriate history and physical examination meeting the standard of care, a diagnosis established through accepted practices, a discussion of the diagnosis and treatment options to obtain informed consent,…
- All 7 cited rules: Mississippi good-faith exam →
- Is an exam required before a patient can be treated in Mississippi? →
- Can the pre-treatment exam be done by telehealth in Mississippi? →
- Must someone be on site while a patient is treated in Mississippi? →
- Can a med spa in Mississippi offer compounded semaglutide or tirzepatide? →
Ownership & corporate practice of medicine6 cited rules
A professional corporation may issue shares only to individuals authorized to render the professional service in its articles, to professional corporations and partnerships so authorized, or to others the licensing authority expressly permits; it exists solely to render professional services within a single…
RN / NP scope for injectables10 cited rules
Registered-nurse practice includes executing the medical regimen, including administering medications and treatments prescribed by a licensed physician or dentist, and excludes medical diagnosis and prescribing except as the Board of Nursing provides by rule; licensed practical nursing is performed under the…
Med-spa registration & licensing18 cited rules
Mississippi licenses the practitioner and registers the physician’s office for two things, surgery and dispensing; the sections cited here contain no medical-spa license. a physician performing Level II or Level III office surgery must register with the State Board of Medical Licensure. The rule defines surgery generally to include any operative procedure using lasers and any elective aesthetic or cosmetic procedure; how the Level II and Level III tiers themselves are drawn is not stated in the sections cited here. A physician who dispenses must obtain a certificate from the medical board after ten hours of pharmacology or dispensing education, then a dispensing physician facility permit from the Board of Pharmacy for each location at $300 a year, and must personally dispense; a physician dispenser may not offer compounded products for resale or dispense another practitioner’s or a pharmacy’s compounded product, though compounding for immediate administration is not prohibited. A pharmacy may compound patient-specific medications for office administration by a practitioner but may not offer compounded products to practitioners for resale, and a compounding pharmacy may sell a limited volume to a practitioner for office use. A cosmetology salon and each practitioner must be licensed by the cosmetology board, whose fees are set in dollars in both the statute and its rule: $50 for a practitioner, $85 for a salon application and inspection, $60 for a salon renewal. The medical board’s published schedule charges $550 for a physician or physician assistant initial license and $300 for annual renewal, the statutory ceiling; the nursing board charges $100 for the RN examination, $100 for active renewal, and $100 for controlled-substance prescriptive authority, initial or renewal.
Office surgery is defined as surgery which is performed outside a hospital, an ambulatory surgical center, abortion clinic, or other medical facility licensed by the Mississippi State Department of Health or a successor agency. Physicians performing Level II or Level III office based surgery must register with the Mississippi State Board of Medical Licensure. That office-surgery registration and the practitioner licenses are the only registrations Title 73, chapter 25 and the Board’s Part 2635 require of a physician’s office; Mississippi issues no license or registration specific to a medical spa. A salon where esthetics is practiced is licensed under the cosmetology chapter.
Miss. Admin. Code Title 30, Part 2635, Rule 2.2(D) (Title 73, ch. 25 and Part 2635 surveyed)
Surgery is defined as any operative procedure, including the use of lasers, performed upon the body of a living human being for the purposes of preserving health, diagnosing or curing disease, repairing injury, correcting deformity or defects, prolonging life, relieving suffering or any elective procedure for aesthetic, reconstructive or cosmetic purposes, to include, but not be limited to: incision or curettage of tissue or organ; suture or other repair of tissue or organ, including a closed as well as an open reduction of a fracture; extraction of tissue including premature extraction of the products of conception from the uterus; insertion of natural or artificial implants; or an endoscopic procedure.
No person required by this chapter to have a license shall conduct a school of any profession regulated by the board, salon or barber shop, or practice cosmetology, barbering, esthetics, nail technology, or practice as an instructor, unless such person has received a license or temporary permit therefor from the board.
The cosmetology board’s fee rule sets its license fees in dollars: A. Practitioner license/renewal $50.00; G. Salon/barber shop application and initial inspection $85.00; I. Salon/barber shop renewal $60.00.
The statute itself prices the same fees: The board shall assess fees in the following amounts and for the following purposes: an initial license or renewal for a cosmetologist, barber, nail technician or esthetician at $ 50.00, a salon application and initial inspection at 85.00, and a salon renewal at 60.00.
The State Board of Medical Licensure’s published fee schedule lists the initial license fee as Medical / Osteopathic / Podiatry $550 and the physician assistant initial license as Physician Assistant $550, with an annual renewal of Medical / Osteopathic / Podiatry $300 for physicians.
the license of every person licensed to practice medicine or osteopathy in the State of Mississippi shall be renewed annually. On or before May 1 of each year, the State Board of Medical Licensure shall mail a notice of renewal of license to every physician or osteopath to whom a license was issued or renewed during the current licensing year. The notice shall provide instructions for obtaining and submitting applications for renewal. The State Board of Medical Licensure is authorized to make applications for renewal available via electronic means. The applicant shall obtain and complete the application and submit it to the board in the manner prescribed by the board in the notice before June 30 with the renewal fee of an amount established by the board, but not to exceed Three Hundred Dollars ($300.00). That figure is a statutory ceiling; the amount the Board actually charges is on its fee schedule.
The Board of Nursing’s fee rule sets fees in dollars, including A. Examination 1) Registered Nurses: $100.00, D. Renewal 1) Active: $100.00, and 4) Controlled Substance Prescriptive Authority (Initial and/or Renewal): $100.00.
Physicians who wish to dispense must register with the Board. To obtain a certificate to dispense medications, a physician must first obtain ten (10) hours of Category 1 AMA or AOA approved CME in the area of Pharmacology and/or Dispensing of Medication. After obtaining a certificate from the Board, the physician is then required to register with the Mississippi Board of Pharmacy and obtain the requisite permit(s) to dispense medications. The physician shall be subject to routine inspections by agents and representatives of the Board of Pharmacy, and they shall be subject to all regulations set forth by the Board of Pharmacy regarding the proper handling, labeling, and dispensing of medications. No physician may delegate dispensing authority to another person. A physician must personally dispense the medication.
Pursuant to the medical board’s dispensing rule, every dispensing physician in this State shall obtain a dispensing physician facility permit from the Mississippi Board of Pharmacy for every location where controlled substances or legend drugs are dispensed. The permit is obtained by application accompanied by a fee of Three Hundred Dollars ($300.00) and renewed annually.
Miss. Bd. of Pharmacy Regs. art. XLVII, § 1 (Physician Dispensing Facility Permits)
Pharmacies shall not offer compounded human drug products to practitioners or to other pharmacies for resale or dispensing. Pharmacies may compound patient specific medications for office administration by a practitioner.
Miss. Bd. of Pharmacy Regs. art. XXXI, § 1(E) (Compounding Guidelines)
Among the transactions the pharmacy board’s facility-permit article allows without a wholesale permit is The sale/purchase of a prescription drug or device by a 503a pharmacy to a licensed practitioner for office use, if the total annual dollar volume of these sales/purchases does not exceed five percent (5%) of that pharmacy's total annual prescription sales. In office use is defined as occurring in locations that are not serviced by a pharmacy permit;
Miss. Bd. of Pharmacy Regs. art. XXXII (Pharmaceutical Drug Facility Permits)
A physician dispenser shall not offer compounded human drug products to other practitioners or to pharmacies for resale or dispensing. A physician dispenser may not dispense compounded product from another practitioner or that was compounded by a 503A or 503B pharmacy. Nothing in this section prohibits a physician from compounding for immediate administration or requires a physician dispenser to obtain a compounding certificate from the MS Board of Pharmacy for compounding for administration.
Miss. Bd. of Pharmacy Regs. art. XLVII (physician dispenser compounding)
A license for the practice of pharmacy shall be obtained by all persons prior to their engaging in the practice of pharmacy. The chapter does not apply to practitioners licensed in Mississippi who are authorized to dispense and administer prescription drugs in the course of their professional practice.
Every business/facility/pharmacy located in this state that engages in or proposes to engage in the practice of pharmacy to consumers or to a business/entity/pharmacy of the state shall register with the Mississippi State Board of Pharmacy
Mississippi puts the same duty on both sides of a med spa, and the cosmetology version names the premises. Under the Board of Barbering and Cosmetology’s rules, “A licensed practitioner must in writing notify the Board of any change of address and/or establishment affiliation within thirty (30) days of such change.”
Miss. Admin. Code (Bd. of Barbering & Cosmetology) Rule 5.21 (Change of Information Notification)
On the medical side the clock is “immediately”, with thirty days as the outer limit before it becomes a disciplinary matter. “Any physician who is licensed to practice medicine in this state and changes his or her practice location or mailing address shall immediately notify the Board in writing of the change. Failure to notify within thirty (30) days could result in disciplinary action.”
Miss. Admin. Code Part 2610, Rule 1.1 (Bd. of Medical Licensure — Change of Address)
Mississippi requires a pharmacy outside the state that serves people or businesses here to hold a Board permit: “Any pharmacy located outside this state that performs any services included in the definition of the practice of pharmacy for residents or to a business/entity/pharmacy of this state shall be considered a nonresident pharmacy and shall be permitted by the board.” The same provision states that “The board shall establish by rule or regulation the criteria that each nonresident pharmacy must meet to qualify for a nonresident permit.” It also provides that after a permit has been issued, it may not be amended, transferred or reassigned.
Advertising rules6 cited rules
The medical practice act makes flamboyant claims of professional excellence unprofessional conduct.
Disciplinary landscape10 cited rules
The medical board’s grounds and sanctions sit in the medical practice act, and the nursing, pharmacy and cosmetology statutes cited here each add their own. Administering, dispensing, or prescribing an addiction-forming drug outside legitimate practice, and dishonorable or unethical conduct likely to deceive, defraud, or harm the public, are grounds against a physician’s license; the board may deny, reprimand, suspend, limit, or restrict for up to five years, or revoke, and may act on a temporary basis without a hearing when continued practice would be an immediate danger to the public. The Board of Nursing may revoke, suspend, fine, or discipline a nurse for acting inconsistently with patient safety, practicing below accepted standards, or unprofessional conduct under its rules, and practicing nursing without a license is unlawful. The Board of Pharmacy may fine up to $1,000 for a first violation and $5,000 for later ones. Practicing a cosmetology profession without a license is a misdemeanor punishable by a fine of $500 to $1,000, and the cosmetology board may seek an injunction through the Attorney General or its own attorney. Practicing as a physician or surgeon without having first been examined and obtained a license is a crime under § 97-23-43, punishable on a first offense by a fine of $100 to $200 or three to twelve months in the county jail, or both, and on a second offense by a fine of $200 to $500 or one to two years in the penitentiary.
(3) Administering, dispensing or prescribing any narcotic drug, or any other drug having addiction-forming or addiction-sustaining liability otherwise than in the course of legitimate professional practice. (d) Being guilty of any dishonorable or unethical conduct likely to deceive, defraud or harm the public.
The board shall have authority to deny an application for licensure or other authorization to practice medicine in this state and to discipline a physician licensed or otherwise lawfully practicing within this state who, after a hearing, has been adjudged by the board as unqualified due to one or more of the following reasons: (a) Unprofessional conduct as defined in the physician licensure and disciplinary laws, pursuant to Section 73-25-29 ; (b) Professional incompetency in the practice of medicine or surgery; or
it may enter an order imposing one or more of the following: (a) Deny his application for a license or other authorization to practice medicine; (b) Administer a public or private reprimand; (c) Suspend, limit or restrict his license or other authorization to practice medicine for up to five (5) years, including limiting the practice of such person to, or by the exclusion of, one or more specified branches of medicine, including limitation on hospital privileges; (d) Revoke his license or other authorization to practice medicine;
If the board determines that evidence in its possession indicates that a physician’s continuation in practice or unrestricted practice would constitute an immediate danger to the public, the board may take any of the same actions on a temporary basis, without a hearing, which it could otherwise take under Sections 73-25-81 through 73-25-95 following a hearing, provided proceedings for a hearing before the board are initiated simultaneously with such temporary action without a hearing.
The Board of Nursing may revoke, suspend, refuse to renew, fine, or discipline a nurse who Has negligently or willfully acted in a manner inconsistent with the health or safety of the persons under the licensee's care; who Has negligently or willfully practiced nursing in a manner that fails to meet generally accepted standards of such nursing practice; or who Engages in any unprofessional conduct as identified by the board in its rules;
Unlicensed practice of medicine is a crime: if any person shall practice as a physician or surgeon without having first been examined and obtained a license as required by law, he shall, on conviction of the first offense, be punished by a fine of not less than $100 or more than $200, or by imprisonment in the county jail not less than three months or more than twelve months, or both; and on conviction of a second offense by a fine of not less than $200 or more than $500, or by imprisonment in the penitentiary not less than one year or more than two years.
It is unlawful for any person, including a corporation or association, to: Practice or offer to practice nursing as defined by this article unless duly licensed or privileged to practice under the provisions of this article;
The Board of Pharmacy may impose a monetary penalty: For the first violation, a monetary penalty of not more than One Thousand Dollars ($1,000.00) for each violation; For the second violation and subsequent violations, a monetary penalty of not more than Five Thousand Dollars ($5,000.00) for each violation.
The violation of any of the provisions of this chapter, including the use of fraudulent statements to obtain any benefits or privileges under this chapter or practicing one (1) of these professions without a license, except as provided in Section 73-7-27(12) , shall constitute a misdemeanor, punishable in any court of competent jurisdiction at the seat of government, and any person or firm convicted of the violation of any of the provisions of this chapter shall be fined not less than Five Hundred Dollars ($500.00) but not more than One Thousand Dollars ($1,000.00).
If any person, salon, school or other type of business entity engaged in the practice or teaching of the professions regulated by the board violates any of the provisions of this chapter, the secretary of the board, upon direction of a majority of the board and in the name of the board, acting through the Attorney General or an attorney employed by the board, shall apply in the chancery court of the county in Mississippi in which the person or licensee resides or in the county which the person or licensee practices, or the county in which the salon, school, or other type of business entity is located, for an order enjoining such violation or for an order enforcing compliance with the provisions of this chapter.
Current as of Sep 18, 2026. Verify against the linked primary source and consult qualified counsel before acting — rules change and turn on your specific facts.
Who may perform it in Mississippi?
We hold Mississippi’s own written limits for injectable (neuromodulator, dermal filler), microneedling / collagen induction, micropigmentation / permanent makeup, sclerotherapy, mechanical exfoliation (dermaplaning, microdermabrasion) — read at source and cited. Check a licence against a procedure and see the rule it rests on.
Check scope in Mississippi →Mississippi med spa compliance — FAQ
- Where do Mississippi med spa and injectable regulations come from?
- Mississippi med spas and injectors are governed by a mix of state and federal authorities — the Mississippi legislature, and the state's boards of nursing, medicine, and pharmacy, alongside federal bodies like the FDA and the Federal Register. MedSpaRadar monitors all of them for Mississippi and flags what changed in plain language.
- Does the FDA's GLP-1 compounding guidance apply in Mississippi?
- Yes — federal FDA actions on GLP-1 compounding (semaglutide, tirzepatide) apply nationwide, including in Mississippi. We track those federal changes alongside any Mississippi-specific rules so you see the full picture for your practice.
- How do I keep up with Mississippi regulatory changes?
- MedSpaRadar sends a free weekly Brief on what changed across Mississippi, the FDA, and the Federal Register. Members get the exact "what to do" for their states in one daily email. It's regulatory monitoring, not legal advice.
Get Mississippi changes as they publish
We scan the Mississippi legislature and licensing boards daily, plus the FDA and the Federal Register. Free weekly Brief — what changed, in plain language, with the source.
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← All states · MedSpaRadar is regulatory monitoring and reference: it summarizes public laws, regulations and agency actions and links each to its source. It is not legal, medical, or compliance advice, and using it creates no attorney-client relationship. A summary can lag its source or leave out detail, and monitoring itself can be interrupted — so an absence of alerts means nothing reached you, not that nothing happened. Read the cited source, check its effective date, and confirm any change to your operations or clinical practice with qualified health-law counsel and your medical director.